Status:

RECRUITING

The Study of Differences in Eosinophil Function and Subsets in Patients With Eosinophilic Pulmonary Diseases

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Eosinophil Subtype

Eosinophilic Pulmonary Diseases

Eligibility:

All Genders

18-90 years

Brief Summary

The study subjects of this research are patients with eosinophil-associated pulmonary diseases, including eosinophilic granulomatosis with polyangiitis, idiopathic hypereosinophilic syndrome, idiopath...

Eligibility Criteria

Inclusion

  • For Healthy Volunteers: healthy volunteers matching the age and gender of the study subjects
  • For EPD: ① Persistent eosinophil count increase\>1500 per cubic millimeter for more than 6 months. ② Lack of evidence of a secondary cause of eosinophilia is required. ③ Signs and symptoms of end-organ damage presumed to be secondary to eosinophilia

Exclusion

  • Patients with concurrent definitive pulmonary infections, malignancies, or other parenchymal lung diseases;
  • Patients who are unable or unwilling to cooperate with the collection of clinical information (e.g., due to mental disorders, memory impairments, etc.);
  • Patients who are unable to provide informed consent.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06944418

Start Date

January 1 2024

End Date

January 1 2027

Last Update

April 25 2025

Active Locations (1)

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Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730