Status:
COMPLETED
Relation Between Insulinoresistance and Neutrophile to Lymphocyte Ratio in Cardiac Surgery.
Lead Sponsor:
Centre Hospitalier Universitaire de Besancon
Conditions:
Insulin Resistance
Cardiac Surgery Requiring Cardiopulmonary Bypass
Eligibility:
All Genders
18+ years
Brief Summary
The University Hospital of Besançon is conducting a public interest research project called CRYSTAL, who studies the relationship between the Neutrophil to Lymphocyte ratio (NLR) and insulin resistanc...
Detailed Description
Coronary artery bypass graft (CABG) and heart valve replacement surgeries under cardiopulmonary bypass (CPB) are considered high-risk procedures, associated with a morbidity of 14% and a mortality rat...
Eligibility Criteria
Inclusion
- Men and women aged over 18
- Scheduled cardiac surgery
- Blood count the day of admission to the IS
- Subject not objecting to the use of their personal data and/or biological samples
- Affiliation to a French social security scheme or beneficiary of such a scheme
Exclusion
- Immunosuppressive treatment
- Pre-existing corticosteroid therapy
- Hematological pathologies
- Current infection (current antibiotic therapy)
- Active tumor disease
- End-stage renal failure (DFG \< 30 ml/min/1.73m² or on dialysis)
- Severe liver failure (TP \< 50%)
- Diabetics on insulin
- Admission to a care unit other than Thoracic and Cardiovascular Surgery Intensive Care (SI CTCV) in the immediate post-operative period
- Pregnant women, parturients and breastfeeding mothers
- Persons deprived of their liberty by a judicial or administrative decision; persons subject to psychiatric care under constraint; persons admitted to a health or social establishment for purposes other than research
- Minors
- Adults subject to a legal protection measure or unable to express their consent
- Subject without health insurance
- Subject in the exclusion period of another study or provided for by the "national volunteer file"
Key Trial Info
Start Date :
August 25 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 18 2024
Estimated Enrollment :
211 Patients enrolled
Trial Details
Trial ID
NCT06945536
Start Date
August 25 2024
End Date
November 18 2024
Last Update
April 25 2025
Active Locations (1)
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1
CHU Besançon
Besançon, France, 25000