Status:

RECRUITING

Misoprostol Before Caesarean Section

Lead Sponsor:

Kafrelsheikh University

Conditions:

Misoprostol

Respiratory Distress Syndrome (RDS) of Neonate

Eligibility:

FEMALE

20-35 years

Phase:

PHASE4

Brief Summary

The aim of our study is to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal res...

Detailed Description

Caesarean section is one of the most common carried out surgical procedures in modern obstetrics. About 18.5 million caesarean section are conducted yearly worldwide, and 21-33% of all caesarean secti...

Eligibility Criteria

Inclusion

  • Women with indication for elective caesarean section.
  • Age less than 35 years old.
  • Gestational age less than 38 weeks.
  • Gestational age will be confirmed by certain LMP or reliable early ultrasound measurement of crown-rump length.
  • Singleton pregnancy with no major anomalies

Exclusion

  • Any obstetric disorders as preeclampsia and diabetes.
  • Fetus with oligohydramnios, intrauterine growth restriction.
  • Any contraindications to misoprostol like those with previous allergic reaction or hypersensitivity to prostaglandin hemorrhagic disorders, and severe anemia.
  • History of more than or equal 2 previous caesarean section.

Key Trial Info

Start Date :

June 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2025

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT06946914

Start Date

June 1 2024

End Date

August 1 2025

Last Update

May 13 2025

Active Locations (1)

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Kafr El-sheikh University Hospital

Kafr Ash Shaykh, Egypt, Egypt