Status:
COMPLETED
Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction
Lead Sponsor:
Tanta University
Conditions:
Mild Therapeutic Hypothermia
Cardiogenic Shock
Eligibility:
All Genders
50-70 years
Phase:
NA
Brief Summary
The study aimed to assess the effects of mild therapeutic hypothermia (MTH) on vasopressors and inotropes in patients with cardiogenic shock (CS) due to acute myocardial infarction (AMI).
Detailed Description
Cardiogenic shock (CS) is a condition characterized by a severe lack of blood flow to vital organs caused by primary malfunction of the heart, as described by the European Society of Cardiology (ESC) ...
Eligibility Criteria
Inclusion
- Age from 50 to 70 years.
- Both sexes.
- Cardiogenic shock post AMI defined by systolic blood pressure \<90 mm Hg for \>30 minutes or motropes required to maintain a systolic blood pressure \>90 mm Hg in the absence of hypovolemia with signs of pulmonary congestion and signs of impaired organ perfusion defined by at least 1 of the following: altered mental status; cold, clammy skin; urine output \<30 mL/h; or arterial lactate \>2 mmol/L.
- 2\. Intubated and sedated
Exclusion
- Self-ventilated
- Indication for targeted temperature management by current guidelines "out of hospital cardiac arrest with return of spontaneous circulation (ROSC)"
Key Trial Info
Start Date :
October 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06947616
Start Date
October 1 2020
End Date
October 1 2022
Last Update
April 27 2025
Active Locations (1)
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1
Tanta University
Tanta, El-Gharbia, Egypt, 31527