Status:
COMPLETED
Effect of Over-the-counter Analgesics on Postoperative Pain
Lead Sponsor:
Zitelli & Brodland Skin Cancer Center
Conditions:
Pain Management
Eligibility:
All Genders
Phase:
PHASE3
Brief Summary
In 2011, a randomized controlled trial compared acetaminophen, acetaminophen + ibuprofen, and acetaminophen + codeine for post-operative pain relief after Mohs surgery. In this study, the combination ...
Detailed Description
Upon completion of informed consent, enrolled participants will be randomized to one of two treatment groups. Group 1 (intervention group): will receive a one-time, mandatory dose of Naproxen sodium ...
Eligibility Criteria
Inclusion
- Patients undergoing Mohs micrographic surgery with same-day reconstruction on the head/neck
Exclusion
- Second intention wound healing Operative site not on head and neck Self-described allergies to acetaminophen or any non-steroidal anti-inflammatory medication Pre-existing pain condition requiring analgesics History of bleeding or clotting disorder Recent history of upper gastrointestinal bleeding or ulcers Advanced liver disease or renal impairment Pregnancy Current use of anticoagulant (examples: aspirin, clopidogrel, warfarin, apixaban)
Key Trial Info
Start Date :
December 22 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06948513
Start Date
December 22 2022
End Date
June 30 2023
Last Update
April 29 2025
Active Locations (1)
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1
Zitelli & Brodland Skin Cancer Center
Clairton, Pennsylvania, United States, 15025