Status:
RECRUITING
Study of the Impact of HYPOglycaemia on Sarcopenia in CIRrhosis
Lead Sponsor:
Centre Hospitalier Universitaire Dijon
Conditions:
Cirrhosis
Eligibility:
All Genders
18+ years
Brief Summary
Fasting blood glucose is maintained by hepatic production of glucose from glycogenolysis or gluconeogenesis. In cirrhosis, glycogen storage capacity is reduced, with a consequent increase in gluconeog...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age ≥18 years
- Person with oral consent
- Patient with cirrhosis according to the 2021 EASL criteria (1)
- Patient receiving regular six-monthly and systematic monitoring of cirrhosis, according to the European recommendations of the EASL (2), or French recommendations of the TNCD (3) and HAS (4), including a clinical examination, a biological work-up (to calculate the CHILD-PUGH score and monitor alpha-feto-protein), AND requiring imaging to screen for HCC of hepatocellular carcinoma using cross-sectional imaging (by MRI and/or hepatic CT scan).
- Exclusion Criteria:
- Patients with active cancer or treated within the last 6 months
- Patient with an acute episode of cirrhosis decompensation (ongoing antibiotic treatment for an active infection, gastrointestinal bleeding, hepatic encephalopathy, acute alcoholic hepatitis) less than one month old.
- Treatment with systemic corticosteroids, in progress or within the last 3 months
- Patient with organ transplant
- Person not affiliated to or not benefiting from a social security scheme
- Person under legal protection (curatorship, guardianship)
- Person subject to a legal protection measure
- Pregnant or breast-feeding women
- An adult who is incapable or unable to give consent
- Minors
- Patients already included in an interventional study who may interfere with the evaluation of this study.
Exclusion
Key Trial Info
Start Date :
September 9 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06948656
Start Date
September 9 2025
End Date
October 1 2027
Last Update
September 16 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHU Dijon Bourgogne
Dijon, France, 21000