Status:
COMPLETED
Brain Death and Organ Donation in Tunisian Intensive Care Units
Lead Sponsor:
Faculty of Medicine, Sousse
Conditions:
Brain Injury
Coma
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study was to identify factors associated with the progression to brain death in critically ill patients with severe brain injuries in Tunisian intensive care units (ICUs...
Detailed Description
Background Brain death (BD) is a legally and medically recognized condition under which organ donation may occur. However, organ donation rates in Tunisia remain low compared to international benchma...
Eligibility Criteria
Inclusion
- Adults ≥18 years admitted to ICU with:
- Severe coma (Glasgow Coma Scale ≤8)
- Requiring mechanical ventilation
- Primary diagnosis of:
- Traumatic brain injury (TBI)
- Hemorrhagic stroke
- Other severe neurological conditions (anoxic brain injury, etc.)
- Potential organ donor status (for brain death subgroup):
- Meets clinical brain death criteria (absent brainstem reflexes, apnea)
Exclusion
- Non-neurological terminal conditions: e.g., Advanced cancer
Key Trial Info
Start Date :
November 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 25 2023
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT06948669
Start Date
November 1 2022
End Date
November 25 2023
Last Update
April 29 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia
Sousse, Tunisia, 4002