Status:

NOT_YET_RECRUITING

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

High Myopia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In this cros-sectionnal study the aim is to increase the understanding of posteria staphyloma through a unique European consortium. Therefore, all eligible patients that either visit the outmatient cl...

Detailed Description

Main objective: To characterize the phenotype and biology of myopic staphyloma in a European population (three countries involved). Main evaluation criterion: To collect a cohort in France of Caucas...

Eligibility Criteria

Inclusion

  • Adults with high myopia (axial length ≥ 26.00 mm or degree of myopia of at least -6 diopters), with and without posterior staphyloma
  • Adults aged 18 years or over
  • Patient with high myopia (axial length ≥ 26.00 mm or degree of myopia of at least -6 diopters), with good quality retinal imaging
  • Patient who has signed a consent form to participate in the study
  • Patient who is a beneficiary of a social security scheme or who is entitled to it

Exclusion

  • Any systemic or ocular pathologies with an impact on the posterior segment of the eye
  • Patient with a systemic pathology likely to affect the posterior segment of the eye:
  • Diabetes
  • Systemic inflammatory disease: sarcoidosis, rheumatoid arthritis, systemic lupus erythematosus, Horton's disease
  • Patients with retinitis pigmentosa
  • Patients with syndromic myopia
  • Patients with myopia associated with a genetic disease such as hereditary vitreoretinopathy
  • Patients under guardianship, curatorship or legal protection, as well as pregnant or breastfeeding women (article L1121-5 of the CSP).

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06949579

Start Date

June 1 2025

End Date

March 1 2027

Last Update

April 29 2025

Active Locations (1)

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1

Cochin Hospital

Paris, France, 75014