Status:
ENROLLING_BY_INVITATION
Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC)
Lead Sponsor:
Ellis Medicine
Conditions:
Chemotherapy-related Cognitive Impairment
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
This randomized clinical trial aims to evaluate the impact of a structured low-intensity exercise program on cognitive function in adult cancer patients undergoing chemotherapy. The study enrolls 100 ...
Detailed Description
Chemotherapy-related cognitive impairment (CRCI) is a well-documented side effect of cancer treatment, yet its underlying mechanisms remain poorly understood and effective interventions are lacking. E...
Eligibility Criteria
Inclusion
- • Age 18 years and older.
- Patients with histologically confirmed malignancy who are planning on receiving chemotherapy.
- Able and willing to provide written informed consent.
- ECOG performance status less than or equal to 2.
- Patients willing and able to perform the exercise as directed.
- Patients with the ability to walk without use of an assistive device.
- Patients with no underlying psychiatric disorder (other than depression, as long as there has been no acute presentation within 6 months of being enrolled in the study).
Exclusion
- • Under the age of 18 years.
- Patients unable to provide informed consent.
- Patients who are non-ambulatory or who have a physical disability preventing exercise.
- ECOG performance status greater than 2.
- Patients with a psychiatric diagnosis (other than depression)
- Patients with a diagnosis of dementia of any type.
- Patients with a neurologic disorder that one could reasonably assume to have an underlying cognitive impairment.
- Patients with a history of traumatic brain injury.
- Patients who will be on chemotherapy for longer than 6 months
Key Trial Info
Start Date :
June 9 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 20 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06950190
Start Date
June 9 2025
End Date
February 20 2027
Last Update
August 12 2025
Active Locations (1)
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1
Ellis Medicine/Roswell Park Medical Oncology
Schenectady, New York, United States, 12308