Status:

RECRUITING

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

Lead Sponsor:

University of Chicago

Conditions:

Cirrhosis, Liver

Diabetes Mellitus Risk

Eligibility:

All Genders

18-75 years

Brief Summary

The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation. The question being a...

Detailed Description

Participants will be enrolled from the liver transplant clinic and will be given a continuous glucose monitor, a wrist actigraph, a home sleep apnea testing device, and a questionnaire packet to colle...

Eligibility Criteria

Inclusion

  • Patients presenting to liver transplant clinic with a diagnosis of cirrhosis.
  • Age \>18 yrs.
  • Ability to understand and sign written consent form, or have a legally-authorized representative or proxy who can be approached for consent

Exclusion

  • Patients without consent
  • Patients with implantable cardioverter defibrillator devices or automated implantable cardioverter defibrillator devices will be excluded from the bio-electrical impedance analysis portion of the measurements.
  • Patients with unremovable electrical medical devices or devices that cannot turn off will be excluded from the bio-electrical impedance analysis measurements
  • Pregnant patients
  • Incarcerated patients
  • Patients with a history of type 2 diabetes mellitus diagnosed \> 5 years ago will be excluded from the Oral Glucose Tolerance Test portion of the study

Key Trial Info

Start Date :

March 12 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2031

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06950788

Start Date

March 12 2024

End Date

January 1 2031

Last Update

April 30 2025

Active Locations (1)

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1

University of Chicago Medical Center

Chicago, Illinois, United States, 60637