Status:

RECRUITING

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Lead Sponsor:

University of Chicago

Conditions:

Periprosthetic Fracture Around Prosthetic Joint Implant

Eligibility:

All Genders

18+ years

Brief Summary

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is pres...

Detailed Description

All steps in the protocol will be completed under the standard of care for our hospital's orthopedic joints and trauma surgeons. All patients identified under the inclusion criteria will undergo preop...

Eligibility Criteria

Inclusion

  • Adult patients (\>18 years old) with periprosthetic fractures around primary or revision hip or knee arthroplasty
  • Patients requiring operative management for these fractures (fixation or revision arthroplasty)
  • Patients presenting to the University of Chicago Medical Center during two (2) year period (October 2025 to October 2027)

Exclusion

  • Patients undergoing non-operative management for periprosthetic fractures
  • Any documented or reported history of past prosthetic joint infection of the involved joint
  • Sinus tract at the time of presentation at the involved joint

Key Trial Info

Start Date :

October 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06952738

Start Date

October 1 2025

End Date

October 31 2027

Last Update

December 22 2025

Active Locations (1)

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1

The University of Chicago Medical Center

Chicago, Illinois, United States, 60637