Status:

COMPLETED

Monocyte Distribution Width (MDW): An Early Marker of Sepsis in Patients With Comorbidities

Lead Sponsor:

Hôpital Universitaire Sahloul

Conditions:

Sepsis

Eligibility:

All Genders

18+ years

Brief Summary

In patients with the aforementioned comorbidities, septic conditions are common and associated with high mortality rates. Early diagnosis, along with prompt and appropriate management, has become a ma...

Detailed Description

We will test the effectiveness of MDW in the early diagnosis of sepsis as a factor of decompensation in patients with comorbidities: renal failure, heart failure, and COPD.

Eligibility Criteria

Inclusion

  • Patients aged over 18 years admitted to the emergency department for decompensation of congestive heart failure or renal failure, or exacerbation of COPD.

Exclusion

  • Patients who received antibiotic treatment in the past 7 days, pregnant women, children, non-consenting patients, patients with a history of malignant hematologic disease, polytransfused patients or those who recently received a transfusion, and patients whose MDW was not reported due to ineffective monocyte counting.

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 30 2025

Estimated Enrollment :

325 Patients enrolled

Trial Details

Trial ID

NCT06953154

Start Date

December 1 2023

End Date

June 30 2025

Last Update

August 21 2025

Active Locations (1)

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1

Sahloul University Hospital

Sousse, Tunisia, 4021