Status:
RECRUITING
Mechanisms And Prognosis of Stroke-Heart Syndrome
Lead Sponsor:
Chensheng Pan
Collaborating Sponsors:
National Natural Science Foundation of China
Conditions:
Stroke
Myocardial Injury
Eligibility:
All Genders
18+ years
Brief Summary
The incidence of stroke-heart syndrome following acute stroke, which encompasses both acute ischemic stroke and acute intracerebral hemorrhage, is notably high and is strongly associated with increase...
Eligibility Criteria
Inclusion
- Patients admitted within 48 hours of onset, confirmed by CT/MRI as having a stroke (including acute ischemic stroke and hemorrhagic stroke).
- Moderate-to-severe stroke with NIHSS ≥ 5.
Exclusion
- Previous focal brain injury (such as stroke, brain surgery, traumatic brain injury, etc.).
- Brain dysfunction caused by other major neurological disorders than stroke (such as brain tumors, epilepsy, Parkinson's disease, etc.).
- Transient ischemic attack (TIA) and subarachnoid hemorrhage (SAH).
- History of cardiac diseases (such as coronary heart disease, heart failure, severe arrhythmias, congenital heart disease, cardiac surgery, valvular heart disease, or undiagnosed significant cardiac symptoms).
- Concomitant systemic diseases such as renal failure (eGFR \< 30), autoimmune disorders, severe infections, etc.
- History of dementia, depression, or other psychiatric disorders.
- Poor compliance and inability to cooperate with follow-up.
Key Trial Info
Start Date :
March 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2028
Estimated Enrollment :
658 Patients enrolled
Trial Details
Trial ID
NCT06954103
Start Date
March 1 2025
End Date
April 1 2028
Last Update
May 1 2025
Active Locations (1)
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1
Department of Neurology, Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030