Status:

RECRUITING

3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features

Lead Sponsor:

Shengjing Hospital

Conditions:

Meningioma

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in pa...

Detailed Description

Meningiomas are the most common primary intracranial tumors and are often surgically resectable. However, the intraoperative texture and adhesion of the tumor to surrounding structures vary widely and...

Eligibility Criteria

Inclusion

  • All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort.

Exclusion

  • Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
  • Pregnant women in the first trimester (within three months)
  • Patients with severe claustrophobia or anxiety
  • Patients with severe fever
  • Patients who can not tolerate MRE
  • Patients with vascular malformations and aneurysms.
  • Patients who do not sign an informed consent

Key Trial Info

Start Date :

October 19 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 9 2026

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06955208

Start Date

October 19 2022

End Date

October 9 2026

Last Update

May 2 2025

Active Locations (1)

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Shengjing Hospital

Shenyang, Liaoning, China, 110000