Status:
COMPLETED
Changed Serum Levels of Sirtuin1 and Sirtuin3 and Their Correlations With Sleep Quality and Cognitive Function in the Patients With Chronic Insomnia Disorder
Lead Sponsor:
Chaohu Hospital of Anhui Medical University
Conditions:
Chronic Insomnia Disorder
Eligibility:
All Genders
18-60 years
Brief Summary
The goal of this study is to explore whether mitochondrial dysfunction exists in patients with chronic insomnia disorder. The main questions it aims to answer are : * Do serum mitochondrial markers c...
Eligibility Criteria
Inclusion
- meet the diagnostic criteria of the third edition of the International Classification of Sleep Disorders,26 At the same time, meet the following requirements: ① Duration suffered form insomnia \> 6 months; ② 18-60 years old; ③ Receiving education ≥ 9 years of, without any understanding and hearing impairment; ④ The Pittsburgh Sleep Quality Index (PSQI) \> 7 sores, Hamilton Anxiety Scale-14 (HAMA-14) \< 14 scores, The Patient Health Questionnaire-9 (PHQ-9) \< 10 scores; ⑤ There was no history of any sedative and hypnotic drugs in the two weeks prior to the visit
Exclusion
- patients during pregnancy or breastfeeding or patients who have taken sedative hypnotic drugs or any other drugs that may affect sleep, mood and cognitive function within two weeks were not eligible for the study.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06955299
Start Date
January 1 2022
End Date
January 31 2024
Last Update
May 2 2025
Active Locations (1)
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1
The Affiliated Chaohu Hospital of Anhui Medical University
Hefei, Anhui, China, 238000