Status:
COMPLETED
Probiotics And Ozonated Olive Oil To Maintain Oral Eubiosis In Stage I And II Periodontitis Patients
Lead Sponsor:
Massimo Corsalini
Conditions:
Periodontal Disease
Periodontal Disease Stage 2
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to investigate the clinical benefits of the combined use of ozonized olive oil products (mouthwash and toothpaste) and probiotics on the health status of patients wi...
Eligibility Criteria
Inclusion
- Male or female, aged between 18 and 70 years of any race.
- Diagnosis of stage I or II periodontitis according to the American Academy of Periodontology and the European Federation of Periodontology 2017 classification of periodontal diseases.
- Good general health.
- Ability to understand and comprehend the study's instructions and sign the informed consent.
Exclusion
- Pregnancy and breastfeeding.
- Periodontal or antibiotic therapy in the last two months.
- Systemic diseases that could influence the severity of periodontal disease or therapeutic success (e.g., Down syndrome, HIV, Diabetes Mellitus).
- Smoking \> 10 cigarettes per day.
- Need for antibiotic prophylaxis for dental procedures.
- Chronic use of anti-inflammatory drugs, calcium channel blockers, antidepressants, and anticonvulsants.
Key Trial Info
Start Date :
January 7 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 24 2024
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT06955546
Start Date
January 7 2023
End Date
July 24 2024
Last Update
May 31 2025
Active Locations (1)
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1
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
Bari, BA, Italy, 70124