Status:
COMPLETED
First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors
Lead Sponsor:
Aarhus University Hospital
Collaborating Sponsors:
Tonix Pharmaceuticals, Inc.
Conditions:
Pain, Face
Eligibility:
All Genders
35-50 years
Phase:
EARLY_PHASE1
Brief Summary
The investigators will test a new positron-emitting radiotracer to determine whether it is suitable for studying the oxytocin receptor by positron emission tomography (PET) in humans. If suitable, the...
Detailed Description
The nine amino acid peptide oxytocin was first isolated in 1927 and is primarily recognised for its hormonal role in uterine contractions, lactation, and social bonding. It has been used to induce lab...
Eligibility Criteria
Inclusion
- Female or male age 35-50 (Women of childbearing potential must use birth control and test negative for pregnancy prior to enrollment in this study).
- Normal anatomy in nasal region evaluated with MRI
- Normal sensory function evaluated with "The Sniffin' Sticks Olfactory Test-Kits
Exclusion
- Pregnancy or breast-feeding.
- Metal implanted in the body.
- Diseases of the nose and airways.
- Former or current cancer in the head/neck area where radiation therapy was applied.
- Former or current brain disease.
- Psychiatric diseases.
- Heart disease.
- Other serious chronic or acute disease.
- Substance abuse disorders.
Key Trial Info
Start Date :
April 30 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2022
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT06955650
Start Date
April 30 2021
End Date
June 30 2022
Last Update
May 2 2025
Active Locations (1)
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1
Aarhus University Hospital
Aarhus, Denmark, 8200