Status:
RECRUITING
Innovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMPACT-INSPIRE)
Lead Sponsor:
National Cancer Centre, Singapore
Collaborating Sponsors:
SingHealth Duke-NUS Academic Medical Centre
Conditions:
Solid Tumor
Eligibility:
All Genders
21-99 years
Brief Summary
This observational study aims to assess the outcomes in patients with advanced treatment refractory cancers with matched molecular/precision therapy as per their molecular profiling results after disc...
Detailed Description
The patient will be observed clinically after informed consent has been obtained. Patients may require more frequent assessment or additional procedures as clinically necessary or as required by the p...
Eligibility Criteria
Inclusion
- Is equal to or greater than 21 years of age;
- Histologic or cytologic confirmed advanced solid tumours;
- Patients who have received and failed all standard anticancer therapy (if available) or are unsuitable for further standard anticancer therapy. Cancers with a poor prognosis or low expected response rate to standard treatment (as judged by the investigator on the basis of available evidence) may be screened with respect to an earlier line of treatment;
- Ability to understand and the willingness to provide written informed consent.
Exclusion
- Specific contraindications to exposure to the off-label or non-standard therapy (as defined by the product label);
- Other comorbid conditions that may compromise assessing key outcomes or, in the judgement of the clinician, limit the ability of the patient to comply with the protocol.
Key Trial Info
Start Date :
September 12 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 12 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06956248
Start Date
September 12 2024
End Date
March 12 2027
Last Update
May 4 2025
Active Locations (1)
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1
National Cancer Centre, Singapore
Singapore, Singapore, 168583