Status:
RECRUITING
Evaluating the Impact of Various Dietary Nitrate Supplements on Oral Health
Lead Sponsor:
Shatha Alhulaefi
Collaborating Sponsors:
Northumbria University
Edith Cowan University
Conditions:
Oral Health
Dietary Nitrate
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study aims to investigate the effects of different dietary nitrate supplements, versus placebo, on microbiological and immunological markers associated with oral health in people aged 18-65 years...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Aged 18 - 65 years.
Exclusion
- Aged less than 18 or more than 65 years old.
- Current smoking
- Alcohol consumption of greater than14 units per week.
- Diagnosis of a chronic disease (e.g., cardiovascular disease, diabetes, cancer, or gastrointestinal disorders), including oral diseases.
- Use of antibiotics within the past three months or medications/nutritional supplements that may affect the oral cavity (e.g., prebiotics, probiotics, or hormone replacement therapy).
- Regular use of antibacterial mouthwash or xylitol-containing products (e.g., gum or toothpaste) or the use of proton pump inhibitors.
- Presence of braces/invisalign or dentures.
- Known allergy to any food, including beets
- Adherence to dietary restrictions (e.g., weight loss diet)
- Eating disorders that may limit participation in the study.
- Currently pregnant, breastfeeding or trying to become pregnant.
- Participation in other studies.
Key Trial Info
Start Date :
May 23 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06956612
Start Date
May 23 2025
End Date
April 1 2026
Last Update
May 28 2025
Active Locations (1)
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1
Newcastle University, Newcastle upon Tyne, Tyne and Wear NE2 4HH
Newcastle, United Kingdom, NE2 4HH