Status:
RECRUITING
Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
Lead Sponsor:
University of Rochester
Conditions:
PTSD
Trauma
Eligibility:
All Genders
8-17 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to test the extent to which different treatment components work to improve pediatric post-traumatic stress disorder (PTSD). It will also provide evidence for how the...
Eligibility Criteria
Inclusion
- A child between the ages of 8-17 exposed to at least one DSM-defined trauma
- Child assent for participation
- The participation of a caregiver with custodial rights to provide parental permission
- Willing to participate in treatment delivery and respond to surveys
- Meet PTSD diagnostic criteria that is the result of exposure to at least one of the identified traumas
- Ability to read and understand English
- Willingness to be randomized to an experimental condition
- Placement in a stable caregiving environment for two months without an impending transition
- Children currently taking psychotropic medications must have taken the medicine without dose adjustment for two months prior to study entry.
- Caregiver or child with a smartphone capable of downloading a freely available software application.
Exclusion
- Psychiatric concerns requiring a higher level of care (e.g. suicidal ideation with intent; current psychotic disorder)
- An intelligence quotient (IQ) \< 70
- Currently receiving a behavioral health intervention for concerns related to PTSD or pediatric trauma
- A participating caregiver who is a perpetrator of any identified trauma (e.g. sexual abuse)
- MRI contraindicators (e.g. presence of metal in the body)
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2028
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06956781
Start Date
January 1 2026
End Date
August 1 2028
Last Update
December 15 2025
Active Locations (1)
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1
The Mt. Hope Family Center
Rochester, New York, United States, 14608