Status:
COMPLETED
The Comparison of Navigational Bronchoscopic and CT-Guided Preoperative Markings in Minimally Invasive Thoracic Surgery
Lead Sponsor:
Semmelweis University
Collaborating Sponsors:
National Institute of Oncology, Hungary
Conditions:
VATS
Lung
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
This clinical trial aims to determine whether navigational bronchoscopic or CT-guided marking is more effective for localizing small pulmonary nodules in minimally invasive thoracic surgery. It will a...
Detailed Description
Two different preoperative markings have proven invaluable for excising smaller pulmonary lesions. Electromagnetic navigation bronchoscopy (NAVIB) provides a more minimally invasive approach, particul...
Eligibility Criteria
Inclusion
- In this study, patients with lung nodules between 10 and 30 mm (under clinical IC or lower stage if it was a case of NSCLC) who are fit for surgery will be enrolled. The investigators will collect epidemiological data, including age, race, gender, Charlson Comorbidity Index, smoking history, medications taken, previous surgeries, significant diseases, BMI, and detailed parameters of the radiological size of the tumor preoperatively. Within two months before surgery, the investigators will conduct a contrast-enhanced chest CT, which will include the upper abdomen and lung function tests (FVC, FEV1, DLCO). Patients who had previous thoracic surgery, are under 18 or over 85 years of age, or have FVC or FEV1 less than 60% will be excluded. Any patient unsuitable for the complete preoperative diagnostic procedure will also be excluded (for example, where contrast material is contraindicated in chronic kidney failure). Pathological parameters of the lesion will be evaluated within four weeks after surgery. Imaging will be conducted at least during the one-month follow-up to monitor complications.
- Summary:
- Aged from 18 to 85
- 1-3 cm lung nodules
- planned procedure VATS uniportal diagnostic wedge
Exclusion
- Previous thoracic surgery
- CCI greater than 12
- Long-term steroid treatment
Key Trial Info
Start Date :
June 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 26 2025
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT06957600
Start Date
June 1 2025
End Date
August 26 2025
Last Update
September 5 2025
Active Locations (1)
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1
Semmelweis University- National Institute of Oncology Department of Thoracic Surgery
Budapest, Budapest, Hungary, 1122