Status:
NOT_YET_RECRUITING
Mechanisms of Mindfulness Meditation and Self-Hypnosis for Pain in Older Adults With Chronic Pain
Lead Sponsor:
University of Washington
Collaborating Sponsors:
The University of Queensland
University of Florida
Conditions:
Chronic Pain
Mindfulness Meditation
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The goal of this study is to better understand how two common psychological treatments for pain work in the brain of older adults living with chronic pain. This study will: 1. evaluate fMRI of adults...
Detailed Description
Research has shown that psychological treatments can help people with chronic pain manage their pain and improve their quality of life. Two common psychological treatments for chronic pain include Min...
Eligibility Criteria
Inclusion
- be ≥60 years of age;
- have self-reported chronic pain (≥3-months, with pain experienced on ≥ 50% of days);
- endorse an average intensity of pain ≥3 on a 0-10 numerical rating scale (NRS) for most days of the previous 3-months;
- be able to read, speak, and understand English;
- be naïve to meditation and hypnosis (\<20-min. practice/week over the past 6-months; never attended a mindfulness or self-hypnosis course); and
- if currently taking analgesic or psychotropic medication, medication must have been stabilized for ≥4-weeks prior to this study.
Exclusion
- have a history of a medical condition that could produce an abnormal EEG (e.g., epilepsy, history of traumatic brain injury);
- have metals in the body (e.g., clips, prosthetics, pace-makers);
- self-report claustrophobia or other contraindications to MRI scanning;
- have uncontrolled hypertension;
- have a primary chronic pain condition of headache;
- show signs of cognitive impairment (6-Item Cognitive Screener during screening; MoCA score at Session 1, using demographically-adjusted normative cut-offs that take into account race, ethnicity, and age);
- have chronic pain due to malignancy (e.g., cancer) or a chronic pain condition for which surgery is recommended and/or planned;
- are currently receiving other psychosocial treatments for any pain condition (as this may influence these treatment results);
- self-report previous participation in an experimental pain study; or
- report \<2 on a 0-10 NRS for pain intensity in response to experimental "heat" pain stimuli (in order to avoid floor effects and to ensure participants are not too insensitive to thermal pain to reliably produce detectable pain-related brain activation).
Key Trial Info
Start Date :
August 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2029
Estimated Enrollment :
375 Patients enrolled
Trial Details
Trial ID
NCT06957743
Start Date
August 1 2025
End Date
August 31 2029
Last Update
August 19 2025
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