Status:
NOT_YET_RECRUITING
Relation Between Lymphocyte-to-C-Reactive Protein Ratio and Coronary Artery Disease Complexity
Lead Sponsor:
Assiut University
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18-80 years
Brief Summary
Aim(s) of the Research : 1. To assess the relationship between the lymphocyte-to-CRP ratio and CAD complexity as assessed by Syntax score in both emergency (STEMI patients undergoing PPCI) and electi...
Detailed Description
Cardiovascular diseases (CVD) remain the leading cause of mortality globally, responsible for approximately 17.9 million deaths annually, with over 75% occurring in low- and middle-income countries . ...
Eligibility Criteria
Inclusion
- Adults aged 18 to 80 years
- Diagnosed with STEMI undergoing primary PCI within 12 hours of symptom onset
- Patients undergoing elective PCI with documented coronary artery disease
- Provided written informed consent
Exclusion
- Previous history of myocardial infarction, PCI, or coronary artery bypass grafting (CABG)
- Diagnosed autoimmune or chronic inflammatory disorders
- Active infection or malignancy at the time of presentation
- Severe renal impairment (eGFR \<30 mL/min/1.73 m²) or hepatic dysfunction
- Use of immunosuppressive therapy
- Diagnosis of acute or chronic leukemia within the past 6 months
Key Trial Info
Start Date :
June 3 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 10 2026
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT06958562
Start Date
June 3 2025
End Date
April 10 2026
Last Update
May 6 2025
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