Status:
RECRUITING
Adjunctive Effect of Erythritol on Pocket Closure Rates
Lead Sponsor:
University of L'Aquila
Conditions:
Periodontitis
Pocket, Periodontal
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants wit...
Detailed Description
This study is testing whether erythritol powder, used during non-surgical periodontal treatment (also known as deep cleaning), can help improve gum health in people with advanced periodontitis (stage ...
Eligibility Criteria
Inclusion
- Adults aged 18 years or older
- Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification
- Presence of at least 12 natural teeth
- Presence of periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth
- Good general health or stable systemic conditions (e.g., controlled diabetes)
Exclusion
- Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment
- Periodontal treatment in the previous 6 months
- Pregnancy or breastfeeding
- Current smokers of more than 10 cigarettes per day
- Allergies or intolerance to erythritol or any materials used in the treatment
- Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency)
- Use of medications known to affect periodontal tissues (e.g., phenytoin, cyclosporine, calcium channel blockers)
Key Trial Info
Start Date :
November 8 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT06958874
Start Date
November 8 2024
End Date
December 31 2025
Last Update
May 6 2025
Active Locations (1)
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1
University of L'Aquila
L’Aquila, Italy, 67100