Status:

ACTIVE_NOT_RECRUITING

Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis

Lead Sponsor:

Saglik Bilimleri Universitesi

Conditions:

Hip Fracture of Intertrochanteric Type

Thromboembolic Event

Eligibility:

All Genders

65+ years

Phase:

NA

Brief Summary

Hip fracture is a common and severe disease in elderly patients. The question of the study is whether elderly patients with severe osteopenia have significantly lower levels of the collagen-binding pr...

Detailed Description

In this study, the investigators aimed to prospectively measure the Hsp 47 gene expression levels in patients scheduled for surgery due to intertrochanteric femur fracture and healthy volunteers in th...

Eligibility Criteria

Inclusion

  • \>65 years of age
  • Interthrocanteric femur fracture AO Type 31A1, 31A2, 31A3
  • Patients treated proksimal femoral nail
  • Minor trauma
  • Fracture mobility score 1,2,3,4,5
  • Inial thrombocytes count 150.000-450.000 /µL

Exclusion

  • Body mass index \>40
  • Fracture mobility score 6 (unknown type)
  • stage 4 chronic kidney disease
  • Patients with rheumatological diseases
  • Patients at serious risk of VTE(Venous thromboembolism) (according to the International Society on Thrombosis and Hemostasis, categorization of venous thromboembolism) :
  • Active Hematologic Cancer
  • Antiphospholipid syndrome
  • History of recurrent thrombosis (DVT)
  • Paroxysmal nocturnal hemoglobinuria

Key Trial Info

Start Date :

November 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06959017

Start Date

November 1 2024

End Date

December 1 2025

Last Update

June 5 2025

Active Locations (1)

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1

Prof Dr emil Tascıoglu City Hospital

Istanbul, Şişli, Turkey (Türkiye), 34384