Status:
NOT_YET_RECRUITING
Exercise-based Frailty Intervention in Lung Transplantation (XFIT)
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
University of Pennsylvania
University of North Carolina
Conditions:
Frailty
Lung Tranplant Candidate
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The goal of XFIT study is to measure the safety of an 8-week telehealth-delivered exercise and behavioral training program to treat frailty in lung transplant candidates in their own home. The main qu...
Detailed Description
We will randomize 70 patients who reflect the diversity and spectrum of illness seen in the general lung transplant candidate population to either XFIT or enhanced standard of care. An interventionali...
Eligibility Criteria
Inclusion
- Group 1
- Age 18 - 65 years
- Lung Transplant Candidates
- Speaks English or Spanish
- ≤ 8LPM O2 on 6MWT
- SPPB score ≤ 10
Exclusion
- Lives Alone
- BMI \< 18.0 kg/m2
- Engaged in clinical pulmonary rehabilitation program
- Severe pHTN (RHC mPAP ≥ 30 mmHg or TTE PASP ≥ 60mmHg or moderately/severely reduced RV systolic function on TTE
- Deemed unsafe by site PI
- Group 2
- Inclusion Criteria:
- Age 18 - 75 years
- Speaks English or Spanish
- ≤ 15LPM O2 on 6MWT
- SPPB score ≤ 10
Key Trial Info
Start Date :
July 15 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2029
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06960421
Start Date
July 15 2026
End Date
July 1 2029
Last Update
June 3 2025
Active Locations (4)
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1
University of California,San Francisco
San Francisco, California, United States, 94143
2
Columbia University
New York, New York, United States, 10032
3
University of North Carolina
Chapel Hill, North Carolina, United States, 27599
4
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104