Status:

RECRUITING

Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions

Lead Sponsor:

Izmir Katip Celebi University

Conditions:

Periodontal Diseases

Periodontitis

Eligibility:

All Genders

18-70 years

Brief Summary

In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body. In recent publications, the role of Gra...

Detailed Description

Periodontal disease is characterized by various microbial infections caused by only certain microbial species out of the many types of bacteria present in the oral cavity, with progressive destruction...

Eligibility Criteria

Inclusion

  • Systemically healthy participants.
  • At least twenty permanent teeth present in the oral cavity.
  • Non-smokers.
  • No medication for continuous use.
  • Not pregnant or breastfeeding.

Exclusion

  • Any oral or systemic disease.
  • Regular use of systemic medications.
  • Pregnancy or lactation.
  • Received periodontal treatment within the last 6 months.
  • Use of antibiotics, anti-inflammatory medications, or systemic corticosteroids in the last 6 months.
  • Smokers.

Key Trial Info

Start Date :

August 14 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06961409

Start Date

August 14 2024

End Date

October 1 2025

Last Update

May 7 2025

Active Locations (1)

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Izmir Katip Çelebi University Department of Periodontology

Izmir, Çiğli, Turkey (Türkiye), 35640