Status:
COMPLETED
Assessment of Health Effects of Air Purifier Interventions on Chronic Kidney Disease Patients
Lead Sponsor:
Inha University Hospital
Conditions:
Chronic Kidney Diseases
Particulate Matter
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
This exploratory study investigates the impact of indoor air quality improvement via air purifiers on the health of chronic kidney disease (CKD) patients. A randomized, single-blind, crossover study ...
Detailed Description
Objectives: Recent research has demonstrated that increasing levels of fine particulate matter (PM2.5) are associated with reduced glomerular filtration rates and elevated risks of chronic kidney dis...
Eligibility Criteria
Inclusion
- Patient Group: Patients aged 20 years or older with stage 3 or higher chronic kidney disease (estimated glomerular filtration rate \[eGFR\] \<60 mL/min/1.73 m²).
- Control Group: Individuals aged 20 years or older who have not been told of any kidney function abnormalities based on blood tests within the past year and have never been diagnosed with chronic kidney disease. Baseline labs will be conducted, and only those with an eGFR ≥60 mL/min/1.73 m² will be enrolled. This group includes household members of the patient group or other healthy individuals.
- Individuals who are not currently using a household air purifier.
- Individuals who have consented to participate in the clinical study.
Exclusion
- Patients with stage 5 chronic kidney disease.
- Individuals with a history of chronic obstructive pulmonary disease (COPD), asthma, allergy, cerebrovascular accident (CVA), malignancy (cancer), cardiovascular interventions, or those with an active infection.
- Individuals taking immunosuppressive medications.
- Patients with diabetes or hypertension whose blood sugar and blood pressure are uncontrolled (HbA1c \> 8%, office SBP \> 150 mmHg).
Key Trial Info
Start Date :
April 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06963372
Start Date
April 11 2022
End Date
December 31 2022
Last Update
May 9 2025
Active Locations (1)
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1
Inha University Hospital
Incheon, South Korea, 22332