Status:

RECRUITING

Effectiveness of Computer-Aided Detection Chest X-Ray Screening for Improving Tuberculosis Diagnostic Yield in Chinese Primary Health Care Settings: Study Protocol for a Prospective Cluster Randomized Controlled Trial

Lead Sponsor:

Xuelin Yang

Collaborating Sponsors:

China Medical Board (CMB)

Yichang Center for Disease Control and Prevention, China

Conditions:

Tuberculosis (TB)

Eligibility:

All Genders

15+ years

Phase:

NA

Brief Summary

The global incidence rate and mortality of tuberculosis (TB) pose a challenge to achieving the goals set out in the tuberculosis eradication strategy and the SDGs by 2030. At present, timely and acces...

Detailed Description

Research Plan 1. Questionnaire survey - Collect general baseline characteristics The general data characteristics involved in this study include age, gender, marital status, occupation, income, place...

Eligibility Criteria

Inclusion

  • Eligibility criteria Inclusion criteria
  • Participants must receive medical treatment at the primary healthcare hospitals in Yichang City, Hubei Province, and underwent chest X-ray examinations. The participants have to meet the following criteria:
  • \>15 years old.
  • Appearance of tuberculosis-related respiratory symptoms or signs.
  • Individuals not previous diagnosed with active pulmonary tuberculosis.
  • Capable of completing pathogen examinations and subsequent related inspections.
  • Exclusion criteria
  • Those who meet any of the below criteria will be excluded:
  • Diagnosed with extrapulmonary tuberculosis or latent tuberculosis infection during the current visit.
  • The quality of Chest X-ray images did not meet the standard requirements.
  • Unrecognized identity information participants.
  • Withdrawal Criteria
  • Participants who are lost to follow-up or who do not complete the follow-up period.
  • Participants who experience a sudden and serious illness or choose not to continue participating in the study.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2027

    Estimated Enrollment :

    22000 Patients enrolled

    Trial Details

    Trial ID

    NCT06963606

    Start Date

    September 1 2025

    End Date

    December 31 2027

    Last Update

    December 31 2025

    Active Locations (1)

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    Township Health-care settings in Yichang City

    Yichang, Hubei, China, 443000