Status:

COMPLETED

Examining the Effect of Neuromuscular Exercises on Movement Control in Hip & Knee Osteoarthritis: A Randomised Proof of Concept and Feasibility Study

Lead Sponsor:

University of Southampton

Collaborating Sponsors:

Ashford and St. Peter's Hospitals NHS Trust

Conditions:

Osteoarthritis

Hip

Eligibility:

All Genders

30+ years

Phase:

NA

Brief Summary

This completed study evaluated the effects of a six-week neuromuscular exercise programme on movement control in individuals with hip and/or knee osteoarthritis (OA). The trial also assessed the feasi...

Detailed Description

Osteoarthritis (OA) is a chronic joint condition that significantly impacts mobility, function, and quality of life. Although exercise is strongly recommended in clinical guidelines for managing OA, t...

Eligibility Criteria

Inclusion

  • Adults aged 30 years or older.
  • Clinically diagnosed symptomatic hip and/or knee osteoarthritis (unilateral or bilateral).
  • Meeting the American College of Rheumatology (ACR) clinical criteria for osteoarthritis.
  • Able to safely participate in neuromuscular exercises and movement screening tests.

Exclusion

  • Acute septic arthritis.
  • Inflammatory arthritis (e.g., rheumatoid arthritis).
  • Avascular necrosis of the hip or knee.
  • Recent steroid injections (within the past 3 months).
  • Knee or hip surgery within the previous 12 months.
  • Significant cardiorespiratory or systemic disorders limiting exercise participation.
  • Neurological conditions (e.g., stroke, Parkinson's disease, multiple sclerosis).
  • Body mass index (BMI) greater than 35 kg/m².
  • Severe low back pain restricting activity.
  • Cognitive impairment affecting ability to follow study instructions.
  • Skin conditions affecting lower limbs, preventing safe participation in exercises.
  • Inability to communicate effectively in English or understand the consent information.

Key Trial Info

Start Date :

July 18 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 7 2025

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06963892

Start Date

July 18 2023

End Date

March 7 2025

Last Update

May 9 2025

Active Locations (1)

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1

Ashford & St Peters NHS Hospital

Chertsey, Surrey, United Kingdom, TW15 3AA