Status:

RECRUITING

Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

Lead Sponsor:

Niguarda Hospital

Conditions:

Colo-rectal Cancer

Eligibility:

All Genders

18-40 years

Brief Summary

Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibac...

Detailed Description

Clinicopathological features, and survival data will be pseudo-anonymized and collected through a dedicated ReDCap database by each participating center. Colibactin assessment - FFPE samples will be ...

Eligibility Criteria

Inclusion

  • Patients with diagnosis of colorectal cancer (vEO-CRC: 18-40 years of age), or SO-CRC diagnosed later than age 60;
  • Informed consent signature from alivepatient;
  • Availability of formalin-fixed paraffin embedded (FFPE) tumor samples (5 FFPE 4uM thick slides and 10 FFPE 10 uM thick slides) and/or fresh tumor tissue retrieved from a biopsy or surgical procedure performed as per clinical standard of care.

Exclusion

    Key Trial Info

    Start Date :

    April 17 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 30 2027

    Estimated Enrollment :

    20 Patients enrolled

    Trial Details

    Trial ID

    NCT06965335

    Start Date

    April 17 2024

    End Date

    June 30 2027

    Last Update

    May 11 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    ASST Grande Ospedale Metropolitano Niguarda

    Milan, Milano, Italy, 20162

    Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study | DecenTrialz