Status:
RECRUITING
Early Beta Blocker Administration in STEMI Patients With SCAI B Status
Lead Sponsor:
Tel-Aviv Sourasky Medical Center
Conditions:
ST Segment Elevation Myocardial Infarction (STEMI)
Cardiogenic Shock Post Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is looking at how a medication called beta-blockers (metoprolol) affects patients with a heart attack (STEMI) who are in the cardiac intensive care unit. When patients are admitted to the ...
Detailed Description
A prospective, randomized, double-blind cohort study will be conducted on patients with STEMI who are hospitalized in the cardiac intensive care unit and classified as SCAI B at the time of admission ...
Eligibility Criteria
Inclusion
- Diagnosis of ST-segment elevation myocardial infarction (STEMI) confirmed by ECG, clinical signs, and coronary catheterization.
- Post-catheterization patients classified as SCAI B upon admission to the unit, defined by the presence of tachycardia and/or hypotension without signs of hypoperfusion (i.e., normal lactate levels, normal capillary refill, preserved mental status, and adequate urine output \>0.5 mL/kg/hour).
- Age 18 years or older.
- Mentally competent to provide informed consent, understand the study procedures, and comply with medical recommendations.
Exclusion
- Pregnancy.
- Inability to provide informed consent.
- Evidence of pulmonary edema.
- Bradycardia (heart rate \<60 beats per minute).
- PR interval \>240 milliseconds.
- Second- or third-degree atrioventricular (AV) block.
- Active asthma.
- Known hypersensitivity to metoprolol.
Key Trial Info
Start Date :
May 21 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06967194
Start Date
May 21 2025
End Date
June 1 2027
Last Update
May 28 2025
Active Locations (1)
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1
Tel Aviv Sourasky Medical center
Tel Aviv, Israel