Status:

RECRUITING

Efficacy of Torque Teno Virus as a Biomarker for Predicting Treatment Response of Immune Checkpoint Inhibitor Therapy and Postoperative Outcome in NSCLC Patients

Lead Sponsor:

Medical University of Vienna

Conditions:

NSCLC (Non-small Cell Lung Cancer)

Eligibility:

All Genders

18+ years

Brief Summary

First discovered in 1997 the torque teno virus (TTV) can be found in the vast majority of the human population throughout their lifetime. The TTV levels correlate with infectious diseases and organ re...

Eligibility Criteria

Inclusion

  • \- Histologically or cytologically verified NSCLC stage II-IV (OMD) according to UICC TNM8 edition considered operable in curative intent after neoadjuvant systemic therapy containing immune checkpoint inhibition by local multidisciplinary tumor board (MDT) decision.
  • ECOG \< or = 1 Staging with PET/CT and cMRI/CCT Written informed consent

Exclusion

  • \-

Key Trial Info

Start Date :

September 6 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06967532

Start Date

September 6 2024

End Date

September 1 2026

Last Update

May 13 2025

Active Locations (1)

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1

Medical University of Vienna

Vienna, Austria, 1090