Status:

COMPLETED

Hydrogen-Rich Water and Metabolic Health in Adults: A 12-Week Randomized Trial

Lead Sponsor:

University of Novi Sad, Faculty of Sport and Physical Education

Conditions:

Metabolic Syndrome

Eligibility:

All Genders

30-65 years

Phase:

NA

Brief Summary

The HYDRO-RESPOND trial is a 12-week randomized controlled study investigating the effects of daily hydrogen-rich water (HRW) consumption on body composition and metabolic biomarkers in adults diagnos...

Eligibility Criteria

Inclusion

  • Age 30-65 years
  • Metabolic syndrome (NHS) (at least 3 of the 5 following criteria):
  • Waist circumference of ≥ 102 cm in men and ≥ 88 cm in women
  • Hypertriglyceridemia (≥ 1.695 mmol/L)
  • Low HDL-C (\< 1.04 mmol/dL in men and \< 1.30 mmol/dL in women)
  • High blood pressure (\> 130/85 mmHg)
  • High fasting glucose (\> 6.1 mmol/L)
  • Not physically active
  • Informed consent signed

Exclusion

  • Major chronic disease and acute injuries
  • History of dietary supplement use during the past 4 weeks
  • History of metabolism-modulating pharmaceuticals use during the past 4 weeks
  • No consent to randomization
  • Participation in other studies

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 30 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06968715

Start Date

April 1 2025

End Date

November 30 2025

Last Update

December 22 2025

Active Locations (1)

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Applied Bioenergetics Lab at Faculty of Sport and PE

Novi Sad, Vojvodina, Serbia, 21000