Status:
RECRUITING
Project COMET: Massed Prolonged Exposure for PTSD and SUD
Lead Sponsor:
Rutgers, The State University of New Jersey
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
University of California, San Diego
Conditions:
Posttraumatic Stress Disorder (PTSD)
Substance Use Disorders (SUD)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for ...
Detailed Description
Posttraumatic stress disorder (PTSD) and substance use disorder (SUD) often co-occur. PTSD+SUD comorbidity is associated with more severe PTSD, worse treatment outcomes for substance use, greater suic...
Eligibility Criteria
Inclusion
- Age 18+
- Enrolled in SUD treatment at Gateway Community Services
- Meet DSM-5 criteria for a SUD (Tobacco Use Disorder alone not sufficient for inclusion)
- Meet DSM-5 criteria for PTSD
- Able to give informed consent
Exclusion
- severe cognitive impairment
- current suicidal or homicidal intent requiring immediate treatment
- current unstable psychotic or manic symptoms not attributable to SUD
Key Trial Info
Start Date :
September 2 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2029
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT06968832
Start Date
September 2 2025
End Date
June 30 2029
Last Update
October 27 2025
Active Locations (1)
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1
Gateway Community Services
Jacksonville, Florida, United States, 32204