Status:
ENROLLING_BY_INVITATION
The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy
Lead Sponsor:
University Hospital Dubrava
Conditions:
Fuchs Endothelial Corneal Dystrophy
Cataract
Eligibility:
All Genders
40-90 years
Brief Summary
The goal of this study is to learn if topical ROCK inhibitors protect endothelial corneal cells in patients with glaucoma and Fuchs endothelial corneal dystrophy after cataract surgery. The main quest...
Detailed Description
The purpose of this study is to evaluate the effect of topical Rho-kinase (ROCK) inhibitors on corneal endothelial cells (CECs) after cataract surgery in patients with cataract, glaucoma and Fuchs End...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- age between 40 and 90 years;
- diagnosis of FECD and glaucoma;
- cataract grade II nuclear/cortical or posterior subcapsular (Lens Opacity Classification System III \[LOCS III\].
- Exclusion criteria:
- other anterior segment pathology (pseudoexfoliation syndrome, corneal opacities);
- ocular surface inflammation;
- intraoperative complications (posterior capsular rupture, vitreous loss, IOL not implanted in the capsular bag);
- previous ocular trauma or intraocular surgery
Exclusion
Key Trial Info
Start Date :
April 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06969586
Start Date
April 1 2025
End Date
October 1 2026
Last Update
May 14 2025
Active Locations (1)
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1
University Hospital Dubrava
Zagreb, Croatia, 10000