Status:
NOT_YET_RECRUITING
Current Microsatellite Stability Results in Colon Cancer
Lead Sponsor:
Turkish Society of Colon and Rectal Surgery
Conditions:
Colon Adenocarcinoma
MSI Positive Colorectal Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this prospective observational study is to learn more about how a specific type of DNA repair issue-called mismatch repair deficiency (dMMR)-affects colon cancer in people living in Turkey...
Detailed Description
This is a prospective, multicenter observational study designed to evaluate the distribution and clinical relevance of microsatellite instability (MSI) and mismatch repair (MMR) subtypes in patients u...
Eligibility Criteria
Inclusion
- Patients who have undergone curative-intent surgery for colon adenocarcinoma between June 1, 2025, and May 31, 2026 Surgery performed at a center with \>30 colon cancer surgeries per year Availability of MMR protein immunohistochemistry (IHC) and/or MSI test results from resection specimen and/or preoperative endoscopic biopsy Signed informed consent for participation and data collection
Exclusion
- Non-adenocarcinoma malignancies of the colon (e.g., neuroendocrine tumors, lymphomas) Rectal cancers (defined as tumors within 15 cm of the anal verge on endoscopy or MRI) Incomplete medical or pathological records preventing classification of MMR status
Key Trial Info
Start Date :
June 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2029
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT06971107
Start Date
June 1 2025
End Date
May 31 2029
Last Update
May 14 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
İstanbul Medipol University
Istanbul, Turkey (Türkiye)
2
Koç University
Istanbul, Turkey (Türkiye)