Status:
NOT_YET_RECRUITING
Impact of Vitamin C on Pain Detection and Tolerance Threshold
Lead Sponsor:
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Conditions:
Pain, Acute
Eligibility:
All Genders
18-65 years
Phase:
EARLY_PHASE1
Brief Summary
Non-opioid treatments are increasingly sought after for managing acute pain. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Advil, Motrin, Naproxen) combined with acetaminophen (e.g., Tylenol) ...
Detailed Description
Opioid-free treatments are increasingly sought for acute pain and NSAIDs have become an alternative to treat acute MSK pain and are often administered in addition to acetaminophen. However, NSAIDs can...
Eligibility Criteria
Inclusion
- Age ≥ 18 to 65 years old;
- No acute or chronic pain;
- No pain medication;
- French or English-speaking
Exclusion
- Currently using vitamin C supplements;
- Pain in the last week or active cancer;
- Unavailable for follow-up;
- Allergy to milk (lactose in the placebo), or vitamin C,
- Treated with cyclosporine or warfarin (interaction with vitamin C);
- Pre-existing oxalate nephropathy, liver cirrhosis or hemochromatosis;
- Evidence of joint or overlying skin infection in the areas of testing.
Key Trial Info
Start Date :
June 2 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT06971315
Start Date
June 2 2025
End Date
December 31 2025
Last Update
May 14 2025
Active Locations (1)
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1
Hopital du Sacre-Coeur de Montreal
Montreal, Quebec, Canada, H4J 1C5