Status:
NOT_YET_RECRUITING
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
Lead Sponsor:
Karolinska Institutet
Collaborating Sponsors:
Region Stockholm
Conditions:
Posttraumatic Stress Disorder (PTSD)
Generalized Anxiety Disorder (GAD)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiag...
Detailed Description
Background: Anxiety disorders are highly prevalent, impairing quality of life and contributing to substantial economic burden. A large portion of the affected individuals also fulfill the criteria fo...
Eligibility Criteria
Inclusion
- Age 18 years or above
- Ability to read and speak Swedish
- A principal diagnosis of post-traumatic stress disorder, generalized anxiety disorder, social anxiety disorder, or panic disorder
- At least one additional comorbid diagnosis (one of the above diagnoses, or obsessive-compulsive disorder, or major depressive disorder)
- Patients on psychotropic medication must have been on a stable dose (excluding as-needed medication) for at least six weeks prior to treatment initiation
Exclusion
- Current diagnosis of psychosis, bipolar disorder or moderate to severe substance use disorder
- Medium to high suicide risk
- Psychiatric, somatic or social problems that require primary intervention other than the treatments offered in the study
- Concurrent psychological treatment
Key Trial Info
Start Date :
August 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
114 Patients enrolled
Trial Details
Trial ID
NCT06971692
Start Date
August 1 2025
End Date
December 1 2028
Last Update
May 14 2025
Active Locations (1)
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1
Psykiatri Nordväst and Psykiatri Sydväst, Region Stockholm
Stockholm, Sweden