Status:

RECRUITING

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

Lead Sponsor:

WW International Inc

Conditions:

Obesity and Overweight

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The study compares the effectiveness of three commercial weight management programs. The primary outcome is absolute and percentage weight change at 12-weeks.

Eligibility Criteria

Inclusion

  • 18 years or older
  • BMI ≥27 kg/m²
  • Own a bodyweight scale that they can weigh themselves with during the study
  • Willing and able to comply with study protocol
  • Capable of providing informed consent
  • Able to read and write in English
  • Willing to be randomized
  • Willing to sign a Non Disclosure Agreement

Exclusion

  • Pregnant, lactating, or plans to become pregnant in the next 6 months
  • Previous bariatric surgery or planned bariatric surgery during the study period
  • Major surgery within the past 6 months or plans to have surgery during the study period
  • Participation in the previous 3 months or current participation in a structured behavioral weight loss program
  • Participation in another structured weight loss program during the study period (i.e., the next 3 months)
  • Communication needs that would render them unable to understand the study and/or intervention materials
  • Current or previous history of anorexia or bulimia nervosa
  • Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight
  • Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months
  • Weight loss of ≥ 5 kg (11 lb) in the previous 6 months
  • Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis
  • Participants who are involved in any other research studies at this time
  • Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
  • Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable)
  • History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months
  • Diagnosis of type 1 or type 2 diabetes
  • Presence of implanted cardiac defibrillator or pacemaker
  • History of cancer within past 5 years or current treatment for cancer
  • Hospitalization for psychiatric disorders during the last 12 months

Key Trial Info

Start Date :

May 14 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

459 Patients enrolled

Trial Details

Trial ID

NCT06972277

Start Date

May 14 2025

End Date

December 31 2025

Last Update

May 28 2025

Active Locations (1)

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1

WW International, Inc

New York, New York, United States, 10010

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs | DecenTrialz