Status:
RECRUITING
Analgesic Effects of Combined Nalbuphine-bupivacaine Versus Dexamethasone-bupivacaine in Pericapsular Nerve Group Block (PENG) After Hip Surgeries: A Randomized Clinical Study
Lead Sponsor:
Zagazig University
Conditions:
Analgesia, Postoperative
Eligibility:
All Genders
21-65 years
Phase:
NA
Brief Summary
The aim of the study to Evaluate the efficacy of nalbuphine-bupivacaine vs dexamethasone-bupivacaine in ultrasound guided pericapsular nerve group (PENG) block for improving pain management, reducing ...
Detailed Description
1. To measure the time of first request of rescue analgesia and to assess the total amount of rescue analgesic consumption (pethidine) in the first 24 hours post-operatively in each group. 2. To asses...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patients acceptance.
- Age: Adults aged 21-64 years old.
- BMI: 25-30 kg/m2
- Sex: both sexes (males or females).
- Patients undergoing unilateral hip surgery under spinal anesthesia.
- ASA (American Society of Anesthesiologists) physical status classification I to II.
- \*Exclusion criteria:
- Patients with contraindications to regional anesthesia (e.g. local or systemic infections, or severe neurological or muscular disorders or patient on anticoagulant).
- Allergy to study drugs: bupivacaine or nalbuphine or dexamethasone
- Patients with severe cardiovascular, respiratory, renal, or hepatic conditions, uncontrolled diabetes diseases, or those undergoing chronic opioid therapy.
- Psychiatric disorders that hinder informed consent or study participation.
- history of neurological diseases or conditions that would affect the efficacy of nerve blocks (e.g., neuropathy, spinal cord injury, or history of severe muscle weakness).
Exclusion
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT06972654
Start Date
April 1 2025
End Date
January 1 2026
Last Update
May 15 2025
Active Locations (1)
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1
Faculity of medicine, Zagazig university, Zagazig
Zagazig, Egypt