Status:
RECRUITING
HIIT in Sedentary Obese Adults: Effects on Metabolic Risk, Body Composition, and FABP4
Lead Sponsor:
Eastern Mediterranean University
Conditions:
High-Intensity Interval Training
Eligibility:
All Genders
20-35 years
Phase:
NA
Brief Summary
It is aimed to investigate the responses of Fatty Acid Binding Protein 4 (FABP4), which has been discovered as a novel biomarker of obesity and metabolic diseases, to regular exercise training. The a...
Detailed Description
Fatty acid binding proteins are intracellular proteins involved in the transport of fatty acids and are particularly associated with lipolytic activity. These proteins constitute a group of molecules ...
Eligibility Criteria
Inclusion
- Aged between 20 and 35 years,
- BMI between 30 and 35 kg/m²,
- Waist circumference of 90-100 cm for women, 105-110 cm for men,
- Sedentary lifestyle (\<600 MET-min/week),
- Referred by a physician (with a statement confirming no contraindication to exercise)."
Exclusion
- BMI \> 35,
- Pregnancy,
- Cardiovascular Diseases: Individuals with serious cardiovascular issues, such as uncontrolled hypertension, heart failure, coronary artery disease, or a heart attack within the last 6 months, which could pose a risk during exercise.
- Respiratory Diseases: Individuals with chronic respiratory conditions, such as uncontrolled or severe asthma or COPD, who cannot tolerate exercise due to their condition.
- Neurological Disorders: Individuals with neurological issues that limit exercise capacity, such as Parkinson's disease, stroke, or multiple sclerosis.
- Musculoskeletal Issues: Individuals with chronic musculoskeletal problems, particularly knee or hip osteoarthritis, that may increase the risk of pain or injury during exercise.
- Metabolic or Endocrine Disorders: Individuals with uncontrolled metabolic issues, such as diabetes or thyroid disorders, that could cause blood sugar or hormonal fluctuations during exercise.
- Acute Infections or Illness: Individuals with acute infections, fever, or recently undergone surgical procedures.
- Any health condition that may prevent participation in exercise."
Key Trial Info
Start Date :
March 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT06973980
Start Date
March 1 2025
End Date
September 1 2025
Last Update
May 15 2025
Active Locations (1)
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1
Eastern Mediterranean University
Famagusta, Cyprus, 99450