Status:
RECRUITING
Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers
Lead Sponsor:
Ryan L Steinberg
Conditions:
Nephrolithiasis
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life. While family history is a known risk fa...
Eligibility Criteria
Inclusion
- Any patient, aged 18-90 and not incarcerated, under the care of a urologist at UIHC with known kidney stone composition including \>=60% calcium phosphate and baseline 24 hour urine pH of \>=6.3
Exclusion
- \- Any patient over the age of 90 years old, incarcerated or without any evidence of calcium phosphate stone composition
- No struvite component on prior stone analysis
- No bacteria with urease producing organism at time of stone removal
- No history or evidence of systemic acidosis
- No use of acetazolamide, topiramate, zonisamide, valproic acid
- Stage \>=3 CKD (GFR\<60)
- Hepatic disease
- Pregnancy
- History of osteoporosis
Key Trial Info
Start Date :
March 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT06974357
Start Date
March 15 2025
End Date
March 1 2027
Last Update
May 21 2025
Active Locations (1)
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1
University of Iowa
Iowa City, Iowa, United States, 52242