Status:
COMPLETED
Weight Off-loading Training, Cardiovascular Indices, Diabetes
Lead Sponsor:
Umm Al-Qura University
Conditions:
Cardiovascular Disease, Diabetes Mellitus Type 2
Peripheral Vascular Disorder Due to Diabetes Mellitus
Eligibility:
All Genders
60-70 years
Phase:
NA
Brief Summary
Aims: To evaluate the effectiveness of partial weight-bearing during aerobic exercise training on cardiovascular disease risk and peripheral vascular function in patients with type 2 diabetes mellitus...
Detailed Description
Diabetes mellitus (DM) continues as a global alarming epidemic, with an increasingly growing health burden and complications across all socioeconomic levels. Type 2 diabetes mellitus (T2DM) is associa...
Eligibility Criteria
Inclusion
- Type 2 diabetes mellitus patients with 0.6\< ankle brachial index ≤ 0.9, treated only with oral hypoglycemic medications (Biguanide or Sulfonylureas + Biguanide), oral anti-diabetic drugs combination, with stable pharmacological treatment for at least 3 months before the study.
- Cognitively competent patients, able to walk independently with or without walking aids, assuming a Sedentary lifestyle (less than 30 minutes daily activity) during the last 6 months.
- Type 2 diabetes mellitus for more than 10 years, with glycosylated hemoglobin (HbA1c% %) level more than 7%, and fasting glucose level more than 7.0 mmol/L.
- Age range from 60 to 70 years, with normal/ accepted nutritional status (Mini Nutritional Assessment score more than 11).
Exclusion
- The following condition resulted in the exclusion of the patients from the study at the initial screening stage:
- Patients with Type 1 diabetes, younger than 60 or older than 70 years.
- Participation in any previous training program or diet regimen within the last 6 months.
- Patients with disturbed nutritional status (Mini Nutritional Assessment score less than 11).
- Serious musculoskeletal or cardiopulmonary disorders that can affect patient safety or the study results.
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2025
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT06974422
Start Date
August 1 2024
End Date
May 1 2025
Last Update
May 15 2025
Active Locations (1)
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1
Umm Al-Qura University
Mecca, Saudi Arabia