Status:
RECRUITING
Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users
Lead Sponsor:
University of Basel
Collaborating Sponsors:
University Psychiatric Clinics Basel, University of Basel, Basel, Switzerland
Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Conditions:
Driving Under the Influence of Cannabis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The relevance of driving under the influence of cannabis is becoming increasingly important in the context of legalization. However, the measurement of tetrahydrocannabinol (THC) blood concentration i...
Eligibility Criteria
Inclusion
- Experience of smoking cannabis products, on average once a week. This may be in combination with tobacco.
- Age 18-65 years Possession of driving license in at least one of the categories A, B, A1; B1, F, G or M
- Sufficient knowledge of German
- No cannabis inhalation or nicotine consumption on study day
- No alcohol consumption within the last 24 h
Exclusion
- Participation in a trial with investigational drugs within 30 days
- Current or previous major psychiatric disorder (e.g., major depression, schizophrenia spectrum disorder)
- Pregnancy or breastfeeding
- Intake of CYP2C9, CYP2C19, and CYP3A4-inducers in the last 4 weeks before the study visit, e.g. rifampicin (antibiotic), carbamazepine (anticonvulsant), phenobarbital (anticonvulsant), phenytoin (anticonvulsant) or inhibitors, such as amiodarone (class III antiarrhythmic medication), antifungal drugs such as fluconazole, miconazole, voriconazole and itraconazole, antibiotics such as clarithromycin and sulfamethoxazole, ritonavir (protease inhibitor) and grapefruit juice.
- The following conditions: vasopressin deficiency, pituitary tumor, active malignancy, severe hyponatremia requiring treatment, congestive heart failure, liver cirrhosis.
Key Trial Info
Start Date :
December 19 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06975020
Start Date
December 19 2025
End Date
January 1 2027
Last Update
December 26 2025
Active Locations (1)
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1
Insitute of forensic medicine
Basel, Switzerland, 4056