Status:

NOT_YET_RECRUITING

Proactive Immune Tolerance Induction in Chemotherapy for Gynecologic Cancer

Lead Sponsor:

Seoul National University Hospital

Collaborating Sponsors:

Seoul National University Bundang Hospital

Seoul National University Boramae Hospital

Conditions:

Ovarian Cancer

Endometrial Cancer

Eligibility:

FEMALE

19+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate the efficacy of proactive immune tolerance induction of chemotherapy (paclitaxel and carboplatin) for patients with gynecologic cancer. The main questio...

Detailed Description

Proactive immune tolerance induction is applied using an automated infusion pump with a pre-programmed protocol. It follows the same stepwise dosing scheme as conventional desensitization therapy used...

Eligibility Criteria

Inclusion

  • Patients receiving paclitaxel and carboplatin chemotherapy for gynecologic malignancies.
  • Patients with no prior history of hypersensitivity reactions to paclitaxel or carboplatin.
  • Patients who are able to read and voluntarily provide written informed consent.
  • Aged 19 years or older.

Exclusion

  • Patients who do not wish to participate in this study voluntarily.
  • Patients who, in the opinion of the investigator, are unsuitable for participation in this clinical trial.

Key Trial Info

Start Date :

June 25 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2028

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06977594

Start Date

June 25 2025

End Date

May 31 2028

Last Update

June 24 2025

Active Locations (1)

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1

Seoul National University Hospital

Seoul, South Korea, 03080