Status:

COMPLETED

The Objective of This Study Was to Compare and Quantify the Bioavailability of Citrulline Byproducts in Blood Samples and in Urine Samples After a Single Dose of the Assigned Dietary Supplement. The Treatment Arms Containing the Following Molecules: Citrulline HCL and L-Citrulline,

Lead Sponsor:

Vireo Systems, Inc.

Collaborating Sponsors:

Princeton Consumer Research

Conditions:

Bioavailability and AUC

Eligibility:

All Genders

18-64 years

Brief Summary

Citrulline dietary supplements are of interest for improving cardiovascular and exercise performance. The health benefits of citrulline are attributable to its ability to increase arginine levels in t...

Eligibility Criteria

Inclusion

  • healthy and hydrated male or female ages 18-64; agrees to refrain from citrulline-rich foods; able and willing to fast 12 hours prior to baseline visit; willing to have blood and urine collections as dictated in the protocol; females of child bearing age have some type of birth control.

Exclusion

  • female subject is pregnant; allergies or sensitivities to citrulline products; history of losing consciousness during blood collection;past medical history of iron deficiency; history of or current treatment for hypertension, coronary heart disease; or angina pectoris; known kidney function issues or disorders; being treated with ACE inhibitors; cancer diagnosis within 5 years of visit; history of chronic disease.

Key Trial Info

Start Date :

July 13 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 27 2024

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT06977854

Start Date

July 13 2024

End Date

July 27 2024

Last Update

May 18 2025

Active Locations (1)

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Princeton Consumer Research

Raritan, New Jersey, United States, 08869

The Objective of This Study Was to Compare and Quantify the Bioavailability of Citrulline Byproducts in Blood Samples and in Urine Samples After a Single Dose of the Assigned Dietary Supplement. The Treatment Arms Containing the Following Molecules: Citrulline HCL and L-Citrulline, | DecenTrialz