Status:
COMPLETED
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Lead Sponsor:
Saint Andrew Hospital Constanta
Conditions:
Cesarean Section Wound
Platelet-rich Plasma (PRP)
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicin...
Detailed Description
Background: Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regener...
Eligibility Criteria
Inclusion
- Female patients, 18 to 45 years old. Scheduled for elective or emergency cesarean section at the participating center.
- Singleton pregnancy (one fetus). Ability to provide written informed consent. Agreement to comply with the study protocol and follow-up visits at day 7 and day 40 postpartum.
Exclusion
- Known coagulation disorders (e.g., thrombocytopenia, hemophilia). Platelet count below 150,000/μL at the time of enrollment. Use of anticoagulant or antiplatelet therapy within 7 days before surgery. Active infection at the surgical site. History of autoimmune diseases affecting wound healing (e.g., lupus, scleroderma).
- Known keloid formation tendency (optional: include if you want to exclude high-risk scarring profiles).
- Multiple pregnancies (twins, triplets, etc.). Patients participating in another interventional clinical trial could interfere with outcomes.
- Inability to follow up for the postoperative evaluations at 7 and 40 days. Refusal to consent or withdrawal of consent at any point
Key Trial Info
Start Date :
February 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06978010
Start Date
February 1 2023
End Date
January 31 2024
Last Update
May 21 2025
Active Locations (1)
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1
Saint Andrew Hospital
Constanța, Constanța County, Romania, 900591