Status:
NOT_YET_RECRUITING
Endoscope-assisted Flapless Approach Versus Papillary Preservation Technique in Periodontal Regeneration.
Lead Sponsor:
The University of Hong Kong
Conditions:
Periodontitis
Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Eligibility:
All Genders
Phase:
NA
Brief Summary
The standard of care for regeneration of lost periodontal tissue from disease at contained defect sites non-responding to non-surgical periodontal therapy is periodontal regenerative surgery. The clas...
Eligibility Criteria
Inclusion
- Stage III - Stage IV Periodontitis patients, 3-4 months after completing steps I \& II periodontal therapy.
- At least 1 tooth presented with 1 site with \>5mm residual PPD and ≥6mm CAL, with ≥3mm intra-osseous defect presented involving predominantly the interdental space of the tooth and presented on paralleling periapical radiographs and/or CBCT.
- Presence of a periodontally stable tooth with PPD≤3mm immediate adjacent to the intra-bony defect of the investigated tooth
- Good Oral Hygiene, with Full Mouth Plaque Score ≤25% at baseline and with good plaque control at proposed surgical field.
Exclusion
- Pre-study period
- Any systemic condition which prevents following the study protocol;
- Any systemic condition which may affect healing outcomes of patients, e.g. uncontrolled or poorly controlled diabetes, unstable or life-threatening conditions or those requiring antibiotic prophylaxis;
- Patients under long-term analgesic medication;
- Current smokers;
- Self-reported pregnancy;
- Systemic antimicrobial therapy within 3 months;
- Teeth that concurrently present with a buccal and a lingual intrabony defect component;
- Tooth with hopeless prognosis or questionable prognosis associated with endodontic lesions, or subgingival restorations that preclude clinical measurements, or excessive uncontrolled mobility;
- Any factors which prohibit regular performance of plaque control around surgical sites;
- Inadeduate oral hygiene with full mouth plaque score \>25%
- Furcation involved surfaces
- During study period -Non-compliance with study protocol
Key Trial Info
Start Date :
January 2 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2029
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT06978036
Start Date
January 2 2026
End Date
August 1 2029
Last Update
May 18 2025
Active Locations (1)
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1
The University of Hong Kong
Hong Kong, Hong Kong