Status:

RECRUITING

Effect of Same-session EUS on ERCP in Pancreaticobiliary Diseases

Lead Sponsor:

Qilu Hospital of Shandong University

Conditions:

Pancreaticobiilary Diseases

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a single-center randomized controlled trial. Eligible subjects meeting inclusion/exclusion criteria will be randomized 1:1 to EUS+ERCP group or ERCP group. Clinical data and patient-reported o...

Eligibility Criteria

Inclusion

  • Patients aged ≥18 years;
  • Patients with pancreaticobiliary diseases definitively indicated for ERCP (as confirmed by HBP Specialists );
  • No prior history of ERCP;
  • No pancreaticobiliary EUS examinations within the preceding 3 months.

Exclusion

  • Patients with clinically confirmed malignant lesions deemed surgically unresectable by multidisciplinary evaluation and requiring pathological diagnosis exclusively for chemotherapy/radiotherapy guidance;
  • Patients with confirmed diagnosis requiring only palliative biliary/pancreatic stent placement for obstructive jaundice ;
  • Patients with anatomical alterations or surgical history affecting EUS feasibility;
  • Severe systemic illness including severe hepatic, renal, cardiopulmonary and cerebrovascular diseases with high risk for endoscopic procedures;
  • Contraindication to iodinated contrast media (allergy or renal impairment preventing ERCP);
  • Pregnancy or lactation;
  • Patients with severe coagulopathy;
  • Declined informed consent;
  • Severe psychiatric disorder/non-cooperation precluding safe procedure.

Key Trial Info

Start Date :

June 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

214 Patients enrolled

Trial Details

Trial ID

NCT06978231

Start Date

June 10 2025

End Date

April 1 2027

Last Update

September 9 2025

Active Locations (1)

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Qilu Hospital of Shandong University

Jinan, Shandong, China, 250000

Effect of Same-session EUS on ERCP in Pancreaticobiliary Diseases | DecenTrialz